The Importance of Small and Low Volume Dispensing


IVEK Small and Low Volume Dispensing Systems Are Trusted Industry Wide


Small volume dispensing and low volume liquid handling and dispensing are often used interchangeably, but there can be subtle differences depending on the context. For example:

  • Small Volume Dispensing typically refers to dispensing very small, precise amounts (often in the microliter or nanoliter range).
  • Low Volume Dispensing might imply that the overall amount being dispensed is low, which can sometimes relate more to the process or throughput rather than the absolute size of the dispensed droplets.

Both small and low volume dispensing are critical in various scientific, medical and industrial applications. Small and low volume dispensing involves the precise measurement and transfer of small liquid quantities, typically in the range of microliters (µL) to milliliters (mL) and is is a vital method used in modern laboratories, facilitating precision, efficiency, and cost-effectiveness in various applications.

By understanding the methods, applications, and considerations associated with both small and low volume dispensing, researchers and technicians can enhance their experimental outcomes and contribute to advancements in their respective fields. Continued development in dispensing technologies promises to improve accuracy and automation, further expanding the potential of low volume dispensing in medicine, scientific research and industry.

The importance of small or low volume dispensing and low volume dispensing machines can be summarized in several key areas

  • Precision: Many biological and chemical assays require exact volumes for accurate results. Low volume dispensing minimizes variability and increases the reliability of experimental outcomes.
  • Cost-Effectiveness: Handling small volumes reduces the consumption of reagents, which can be particularly beneficial when dealing with costly materials or rare compounds.
  • Reduced Waste: Lower volumes lead to less waste generation, which is increasingly important for environmental sustainability and regulatory compliance.
  • Automation Capability: Low volume dispensing can be easily integrated into automated systems, enhancing throughput and efficiency in laboratory workflows.

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Key Considerations in Low Volume Dispensing

Low-volume dispensing, especially in precision applications like pharmaceuticals, biotechnology, and microelectronics, requires careful attention to ensure accuracy, repeatability, and efficiency.IVEK's Single Channel Small, Low Volume Dispensing systems offer precision and repeatablilty. These systems are easily used in a manual, semi-automated or fully integrated manufacturing process. Keep in mind these considerations:

  • Calibration and Maintenance: Regular calibration of dispensing equipment is essential to maintain accuracy. Users should follow manufacturer guidelines for maintenance.
  • Environmental Factors: Always be aware of the environment that dispensing occurs in. Temperature, humidity, and viscosity of the liquid can affect dispensing accuracy. Laboratories should control these factors to ensure reliable results.
  • User Technique: Training users in proper pipetting techniques can significantly improve accuracy. Factors such as speed, angle, and immersion depth can impact results.
  • Choice of Equipment: Selecting the appropriate dispensing method based on the specific application and volume requirements is crucial for successful outcomes.

Applications of Low Volume Dispensing

Low volume dispensing finds application across various fields, including:

  • Pharmaceutical Development: In drug formulation, precise dispensing of solvents, active pharmaceutical ingredients (APIs), and excipients is crucial for creating effective medications. Low volume techniques ensure the correct ratios are maintained during formulation.
  • Biotechnology: In assays like ELISA (Enzyme-Linked Immunosorbent Assay) and PCR (Polymerase Chain Reaction), low volume dispensing is necessary for reagent preparation. Accurate pipetting can influence the sensitivity and specificity of the assays.
  • Environmental Testing: Low volume dispensing is used in the analysis of environmental samples, such as soil and water, where precise measurements are critical for detecting contaminants.
  • Food and Beverage Industry: Quality control in food production often requires the accurate dispensing of additives and flavorings. Low volume dispensing ensures consistency and compliance with safety standards.